VULVODYNIA

This study tests a single dose of a drug called pudafensine to see if it can reduce pain in women with provoked vestibulodynia, a type of chronic vulvar pain. About 24 women will receive either the drug or a placebo in random order, and researchers will measure pain thresholds in…

This study tests a cream called ketotifen fumarate for women with secondary vestibulodynia, a condition causing burning or sharp pain during vaginal penetration. About 54 women will apply the cream or a placebo twice daily for 12 weeks to see if it reduces pain and improves quali…

This study tests whether physiotherapy and a special light therapy (photobiomodulation) can reduce pain in women with provoked vestibulodynia, a common cause of pain during sex or tampon use. 240 women will be assigned to one of four groups: light therapy, sham light therapy, phy…

This study is creating a database to better understand vaginal conditions such as vulvodynia, yeast infections, bacterial vaginosis, and preterm labor. Researchers will look at proteins, immune markers, and vaginal bacteria in 550 women, including healthy volunteers and those wit…