VASCULAR ANOMALY
Clinical trials for VASCULAR ANOMALY explained in plain language.
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Cancer drug shows promise for rare blood vessel disorders
Disease control OngoingThis phase 2 trial tests the drug trametinib in 45 people aged 2 months to 30 years with vascular anomalies caused by changes in the Ras/MAPK pathway. Participants take trametinib daily for up to 3 years. The study measures whether the drug shrinks lesions, improves quality of li…
Matched conditions: VASCULAR ANOMALY
Phase: PHASE2 • Sponsor: Children's Hospital of Philadelphia • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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Cancer drug shows promise for rare blood vessel disorders in kids and young adults
Disease control OngoingThis study tests the drug alpelisib, already approved for some breast cancers, in people aged 2 months to 30 years with certain blood vessel growth disorders caused by PIK3CA or TIE2 gene changes. Participants take the drug for 2-3 years and attend up to 16 clinic visits to check…
Matched conditions: VASCULAR ANOMALY
Phase: PHASE2 • Sponsor: Children's Hospital of Philadelphia • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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New imaging technique could shed light on lymphatic disorders
Diagnosis ENROLLING_BY_INVITATIONThis study uses a special camera and a safe dye to take pictures of the lymphatic system, which helps move fluid in the body. Researchers want to see how this system works in healthy people and in those with conditions like lymphedema or lipedema. The goal is to find patterns tha…
Matched conditions: VASCULAR ANOMALY
Sponsor: The University of Texas Health Science Center, Houston • Aim: Diagnosis
Last updated Jun 27, 2026 11:00 UTC