TP53
Clinical trials for TP53 explained in plain language.
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Promising drug duo aims to stall recurrent uterine cancer
Disease control Recruiting nowThis study tests whether two drugs, abemaciclib and letrozole, can help keep advanced or recurrent endometrial cancer from progressing. The trial enrolls 32 people with a specific type of cancer (ER-positive, mismatch repair proficient, TP53 wildtype). Participants take the drugs…
Matched conditions: TP53
Phase: PHASE2 • Sponsor: Dana-Farber Cancer Institute • Aim: Disease control
Last updated May 17, 2026 08:04 UTC
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New stem cell method aims to cut transplant complications in blood cancer patients
Disease control Recruiting nowThis study tests a new way to prepare stem cells for transplant in children and adults with blood cancers like leukemia. The method removes certain immune cells to lower the risk of graft-versus-host disease, a serious side effect. About 70 participants will receive the treatment…
Matched conditions: TP53
Phase: PHASE2 • Sponsor: Masonic Cancer Center, University of Minnesota • Aim: Disease control
Last updated May 17, 2026 08:00 UTC
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New hope for aggressive lymphoma with gene mutation?
Disease control Recruiting nowThis study tests a combination of three drugs (glofitamab, a PD-1 inhibitor, and lenalidomide) in 24 people with a type of large B-cell lymphoma that has returned or not responded to treatment and has a specific gene change (TP53). The goal is to see if this combination can shrin…
Matched conditions: TP53
Phase: PHASE2 • Sponsor: The First Affiliated Hospital with Nanjing Medical University • Aim: Disease control
Last updated Apr 30, 2026 15:51 UTC