T2DM
Clinical trials for T2DM explained in plain language.
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New combo pill aims to tackle diabetes and fatty liver at once
Disease control Not yet recruitingThis phase 4 trial will test whether adding alogliptin to a standard two-drug regimen (pioglitazone and metformin) improves blood sugar control and liver health in 80 adults with type 2 diabetes and fatty liver disease. Participants must not have used diabetes medications in the …
Matched conditions: T2DM
Phase: PHASE4 • Sponsor: The Fourth Affiliated Hospital of Zhejiang University School of Medicine • Aim: Disease control
Last updated Jun 27, 2026 12:00 UTC
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Popular diabetes drug semaglutide under scrutiny for bone effects
Disease control Not yet recruitingThis study looks at whether semaglutide (a diabetes drug that lowers blood sugar and helps with weight loss) affects bone density and fracture risk in people with type 2 diabetes. About 150 adults aged 50–75 will get either semaglutide plus metformin or metformin alone for 12 mon…
Matched conditions: T2DM
Phase: PHASE4 • Sponsor: The First Affiliated Hospital of Xiamen University • Aim: Disease control
Last updated Jun 26, 2026 17:38 UTC
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Sleep and menopause may harm diabetic women's hearts, study warns
Knowledge-focused Not yet recruitingThis study looks at how menopause and poor sleep change heart structure and function in women aged 48-58 with type 2 diabetes. Researchers will use heart ultrasounds to measure early signs of heart strain. No treatment is given; the goal is to better understand these risks.
Matched conditions: T2DM
Sponsor: Ottawa Heart Institute Research Corporation • Aim: Knowledge-focused
Last updated Jul 03, 2026 00:00 UTC