T2DM
Clinical trials for T2DM explained in plain language.
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New diabetes pill HRS9531 enters Mid-Stage trial – could it help control blood sugar?
Disease control Not yet recruitingThis Phase 2 trial tests whether HRS9531 tablets can improve blood sugar control in people with type 2 diabetes who haven't achieved good control with lifestyle changes or metformin alone. About 240 participants will receive either the drug or a placebo for 20 weeks. The main goa…
Matched conditions: T2DM
Phase: PHASE2 • Sponsor: Fujian Shengdi Pharmaceutical Co., Ltd. • Aim: Disease control
Last updated Jun 27, 2026 12:36 UTC
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Could this pill protect kidneys in diabetes?
Disease control Not yet recruitingThis study tests whether an investigational drug called HTD1801 can slow the worsening of kidney disease in adults who have both type 2 diabetes and chronic kidney disease. About 75 participants will take either HTD1801 or a placebo twice daily for 12 weeks. Researchers will meas…
Matched conditions: T2DM
Phase: PHASE2 • Sponsor: Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences • Aim: Disease control
Last updated Jun 27, 2026 12:01 UTC
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New combo pill aims to tackle diabetes and fatty liver at once
Disease control Not yet recruitingThis phase 4 trial will test whether adding alogliptin to a standard two-drug regimen (pioglitazone and metformin) improves blood sugar control and liver health in 80 adults with type 2 diabetes and fatty liver disease. Participants must not have used diabetes medications in the …
Matched conditions: T2DM
Phase: PHASE4 • Sponsor: The Fourth Affiliated Hospital of Zhejiang University School of Medicine • Aim: Disease control
Last updated Jun 27, 2026 12:00 UTC
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Popular diabetes drug semaglutide under scrutiny for bone effects
Disease control Not yet recruitingThis study looks at whether semaglutide (a diabetes drug that lowers blood sugar and helps with weight loss) affects bone density and fracture risk in people with type 2 diabetes. About 150 adults aged 50–75 will get either semaglutide plus metformin or metformin alone for 12 mon…
Matched conditions: T2DM
Phase: PHASE4 • Sponsor: The First Affiliated Hospital of Xiamen University • Aim: Disease control
Last updated Jun 26, 2026 17:38 UTC
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Sleep and menopause may harm diabetic women's hearts, study warns
Knowledge-focused Not yet recruitingThis study looks at how menopause and poor sleep change heart structure and function in women aged 48-58 with type 2 diabetes. Researchers will use heart ultrasounds to measure early signs of heart strain. No treatment is given; the goal is to better understand these risks.
Matched conditions: T2DM
Sponsor: Ottawa Heart Institute Research Corporation • Aim: Knowledge-focused
Last updated Jul 02, 2026 03:00 UTC