STIFF PERSON SYNDROME
Clinical trials for STIFF PERSON SYNDROME explained in plain language.
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Engineered immune cells take on lupus and scleroderma in early trial
Disease control ENROLLING_BY_INVITATIONThis early-phase study tests a new treatment called Prula-cel for people with autoimmune diseases like lupus, scleroderma, and vasculitis. Prula-cel uses donor immune cells engineered to target and destroy faulty immune cells that attack the body. The goal is to find a safe dose …
Matched conditions: STIFF PERSON SYNDROME
Phase: PHASE1 • Sponsor: Adicet Therapeutics • Aim: Disease control
Last updated Jun 27, 2026 11:02 UTC
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Could a stem cell transplant stop the immune system from attacking the brain?
Disease control OngoingThis phase 2 trial tests whether high-dose chemotherapy followed by a stem cell transplant can stop the immune system from attacking the nervous system in people with autoimmune neurologic diseases like multiple sclerosis and stiff person syndrome. The treatment aims to weaken th…
Matched conditions: STIFF PERSON SYNDROME
Phase: PHASE2 • Sponsor: Fred Hutchinson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 09:08 UTC
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Experimental CAR T-Cell therapy targets rare stiff person syndrome
Disease control OngoingThis phase 2 trial is testing a new treatment called KYV-101 for people with stiff person syndrome (SPS) that hasn't improved with standard therapies. The treatment uses a patient's own immune cells, modified to target and attack certain immune cells that may be causing the disea…
Matched conditions: STIFF PERSON SYNDROME
Phase: PHASE2 • Sponsor: Kyverna Therapeutics • Aim: Disease control
Last updated Jun 27, 2026 08:06 UTC