STAGE IIIC BREAST CANCER
Clinical trials for STAGE IIIC BREAST CANCER explained in plain language.
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New vaccine aims to train immune system against breast cancer stem cells
⭐️ VACCINE ⭐️ OngoingThis early-phase trial tests a DNA vaccine called STEMVAC in 42 people with advanced HER2-negative breast cancer whose disease is stable or gone after standard treatment. The vaccine targets cancer stem cells, which are thought to resist chemotherapy and help cancer spread. The m…
Matched conditions: STAGE IIIC BREAST CANCER
Phase: PHASE1 • Sponsor: University of Washington • Aim: ⭐️ VACCINE ⭐️
Last updated Jun 03, 2026 12:05 UTC
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Can adding a targeted drug shrink breast tumors before surgery?
Disease control OngoingThis study tests whether giving chemotherapy (paclitaxel and cyclophosphamide) with or without the targeted drug trastuzumab before surgery can shrink breast tumors and reduce the amount of tissue that needs to be removed. It includes 92 women with early-stage or locally advanced…
Matched conditions: STAGE IIIC BREAST CANCER
Phase: PHASE2 • Sponsor: University of Nebraska • Aim: Disease control
Last updated Jun 16, 2026 12:49 UTC
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New chemo combo shows promise against tough breast cancer
Disease control OngoingThis study tested a two-drug chemotherapy combination (carboplatin and nab-paclitaxel) given before surgery to people with locally advanced or inflammatory triple negative breast cancer. The goal was to see if this approach could shrink tumors enough to improve the chances of a c…
Matched conditions: STAGE IIIC BREAST CANCER
Phase: PHASE2 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated Jun 12, 2026 12:05 UTC
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New hormone combo tested to shrink breast tumors before surgery
Disease control OngoingThis phase 3 study tests whether a combination of two hormone therapies (fulvestrant and anastrozole) or fulvestrant alone works better than standard anastrozole to shrink estrogen receptor-positive breast cancer before surgery in postmenopausal women. About 1,473 women with stag…
Matched conditions: STAGE IIIC BREAST CANCER
Phase: PHASE3 • Sponsor: Alliance for Clinical Trials in Oncology • Aim: Disease control
Last updated Jun 09, 2026 12:08 UTC
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PET scan may predict breast cancer drug success before surgery
Knowledge-focused OngoingThis study looks at whether a special PET scan using copper Cu64-DOTA-trastuzumab can predict how well HER2-positive breast cancer responds to targeted drugs (trastuzumab and pertuzumab) before surgery. About 18 women with locally advanced breast cancer will receive the scan and …
Matched conditions: STAGE IIIC BREAST CANCER
Phase: PHASE2 • Sponsor: City of Hope Medical Center • Aim: Knowledge-focused
Last updated Jun 12, 2026 12:06 UTC