SOLID NEOPLASM
Clinical trials for SOLID NEOPLASM explained in plain language.
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New combo therapy zaps spine tumors before they paralyze
Disease control OngoingThis study tests a combination of two treatments—heat-based tumor destruction (thermal ablation) and precise high-dose radiation (stereotactic radiosurgery)—for people whose cancer has spread to the spine and is pressing on the spinal cord. The goal is to control the tumor and pr…
Matched conditions: SOLID NEOPLASM
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 17, 2026 02:59 UTC
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Experimental combo targets Hard-to-Treat cancers
Disease control OngoingThis early-phase study tests a new drug called veliparib combined with two chemotherapy drugs (cyclophosphamide and doxorubicin) in people with advanced solid tumors or non-Hodgkin lymphoma that has spread or cannot be removed. The main goal is to find the safest dose and underst…
Matched conditions: SOLID NEOPLASM
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 17, 2026 02:57 UTC
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New hope for kids with rare cancers: drug blocks tumor growth
Disease control OngoingThis study tests a drug called cabozantinib in children and young adults (up to age 30) with rare cancers like sarcomas, Wilms tumor, and others that have come back or not responded to standard therapy. The drug works by blocking enzymes that help tumors grow and form blood vesse…
Matched conditions: SOLID NEOPLASM
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 15, 2026 11:58 UTC
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Tailoring drug doses to fight Hard-to-Treat cancers
Disease control OngoingThis study tests whether adjusting the dose of the drug pazopanib based on each person's blood levels can improve treatment for advanced solid tumors that have spread or stopped responding to standard therapy. About 54 adults with these cancers will receive pazopanib, and researc…
Matched conditions: SOLID NEOPLASM
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 15, 2026 11:54 UTC
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New drug duo targets Hard-to-Treat brain tumors
Disease control OngoingThis early-phase trial tests a new drug (MLN0128) combined with bevacizumab in people with recurrent glioblastoma (a brain cancer) or other advanced solid tumors that have stopped responding to standard treatments. The main goals are to find the safest dose and understand side ef…
Matched conditions: SOLID NEOPLASM
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated May 11, 2026 20:50 UTC
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New drug shows promise for rare childhood cancers
Disease control OngoingThis study tests a drug called larotrectinib in children and young adults with certain cancers that have a specific genetic change called a TRK fusion. The goal is to see if the drug can shrink tumors or control the cancer. About 33 participants with solid tumors or relapsed leuk…
Matched conditions: SOLID NEOPLASM
Phase: PHASE2 • Sponsor: Children's Oncology Group • Aim: Disease control
Last updated May 04, 2026 16:23 UTC
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Cancer testing study pulled before it started
Knowledge-focused TerminatedThis study was designed to look at how community cancer clinics test for biomarkers in common cancers like lung, breast, and colorectal cancer. The goal was to find out if testing is fast and accurate, and to spot any differences in how tests are done. However, the study was with…
Matched conditions: SOLID NEOPLASM
Sponsor: ECOG-ACRIN Cancer Research Group • Aim: Knowledge-focused
Last updated May 17, 2026 02:56 UTC
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Age check: new screening aims to reduce chemo harm in seniors
Knowledge-focused OngoingThis study looks at whether a thorough health review—covering physical, mental, and social well-being—can predict chemotherapy side effects in older adults with solid tumors. Researchers will compare side effects and hospital stays before and after using this assessment. The goal…
Matched conditions: SOLID NEOPLASM
Phase: NA • Sponsor: City of Hope Medical Center • Aim: Knowledge-focused
Last updated May 11, 2026 20:39 UTC