RETINITIS PIGMENTOSA (RP)
Clinical trials for RETINITIS PIGMENTOSA (RP) explained in plain language.
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New drug aims to preserve sight in rare genetic blindness
Disease control Not yet recruitingThis phase 3 trial tests whether NPI-001, taken twice daily for 24 months, can slow the loss of light-sensing cells in the eyes of adults with Usher syndrome, a genetic condition that causes both hearing and vision loss. About 80 participants will receive either the drug or a pla…
Matched conditions: RETINITIS PIGMENTOSA (RP)
Phase: PHASE3 • Sponsor: Nacuity Pharmaceuticals, Inc. • Aim: Disease control
Last updated Jul 02, 2026 03:00 UTC
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Gene therapy injection aims to save sight in rare eye disease
Disease control Not yet recruitingThis early-stage trial tests a single injection of ZM-02, a gene therapy, in 21 people aged 6 to 60 with advanced retinitis pigmentosa, a genetic condition that causes progressive vision loss. Participants are randomly assigned to receive either a low or high dose of ZM-02 or a s…
Matched conditions: RETINITIS PIGMENTOSA (RP)
Phase: PHASE1, PHASE2 • Sponsor: Zhongmou Therapeutics • Aim: Disease control
Last updated Jun 27, 2026 12:06 UTC
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Gene therapy injection aims to slow vision loss in rare eye disease
Disease control Not yet recruitingThis early-stage trial tests a single injection of a gene therapy drug called UGX202 in 6 adults with advanced retinitis pigmentosa, a genetic condition that causes vision loss. The main goal is to check if the treatment is safe and tolerable over 52 weeks. Researchers will also …
Matched conditions: RETINITIS PIGMENTOSA (RP)
Phase: EARLY_PHASE1 • Sponsor: Suzhou UgeneX Therapeutics Co., Ltd. • Aim: Disease control
Last updated Jun 27, 2026 08:07 UTC
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New eye scanner could spot hidden signs of blindness
Diagnosis Not yet recruitingThis study will test a new, non-invasive eye scanner called wide field OCTA in 200 people with various eye diseases, including age-related macular degeneration, diabetic retinopathy, and dry eye. The goal is to see if this device can provide better images of blood vessels in the …
Matched conditions: RETINITIS PIGMENTOSA (RP)
Sponsor: IRCCS San Raffaele • Aim: Diagnosis
Last updated Jun 27, 2026 08:07 UTC
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Scientists track eye disease patterns to speed future cures
Knowledge-focused Not yet recruitingThis study looks back at medical records of 200 people with inherited retinal diseases, like retinitis pigmentosa and Stargardt disease. Researchers will analyze vision tests and eye scans to see how these diseases progress and how genetics affect symptoms. The goal is to find be…
Matched conditions: RETINITIS PIGMENTOSA (RP)
Sponsor: IRCCS San Raffaele • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:02 UTC