RESTLESS LEGS SYNDROME
Clinical trials for RESTLESS LEGS SYNDROME explained in plain language.
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Spine injection may quiet restless legs, small study hints
Symptom relief CompletedThis study looked at whether a lumbar epidural steroid injection can reduce restless legs syndrome symptoms in 45 adults with lumbar central spinal stenosis. Participants received a standard injection as part of routine care, and their restless legs severity, pain, disability, an…
Matched conditions: RESTLESS LEGS SYNDROME
Sponsor: Saglik Bilimleri Universitesi • Aim: Symptom relief
Last updated Jun 27, 2026 13:05 UTC
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Botox injection shows promise for restless legs relief
Symptom relief CompletedThis study tested whether botulinum toxin type A (like Botox) can ease symptoms of restless legs syndrome (RLS) in 27 adults who did not get enough relief from standard treatments. Participants received one injection, and researchers checked if leg discomfort and urge to move imp…
Matched conditions: RESTLESS LEGS SYNDROME
Phase: PHASE2 • Sponsor: University Hospital, Bordeaux • Aim: Symptom relief
Last updated Jun 27, 2026 12:32 UTC
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New drug candidate aims to calm restless legs when current meds backfire
Symptom relief CompletedThis small study tested whether ecopipam, a drug that blocks a specific brain receptor, can help people with restless leg syndrome whose symptoms have gotten worse from their usual dopamine-based medication. Ten adults took either ecopipam or a placebo for six weeks, then switche…
Matched conditions: RESTLESS LEGS SYNDROME
Phase: PHASE1, PHASE2 • Sponsor: William Ondo, MD • Aim: Symptom relief
Last updated Jun 27, 2026 12:24 UTC
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Could iron pills ease ADHD and restless legs in children?
Symptom relief CompletedThis study looked at whether giving iron supplements to children with ADHD, restless legs syndrome, and low iron levels could improve their symptoms. Twelve kids aged 10-15 took iron for 3 months. Researchers measured changes in brain iron, blood iron, and symptoms using sleep mo…
Matched conditions: RESTLESS LEGS SYNDROME
Sponsor: Hugo W. Moser Research Institute at Kennedy Krieger, Inc. • Aim: Symptom relief
Last updated Jun 27, 2026 07:54 UTC
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Jaw pain linked to restless legs and poor sleep, new study finds
Knowledge-focused CompletedThis study looked at 102 adults to see how common restless legs syndrome is in people with temporomandibular joint (jaw) disorders. Researchers also checked if having both conditions affects sleep quality and daily life. Participants filled out questionnaires about their symptoms…
Matched conditions: RESTLESS LEGS SYNDROME
Sponsor: Gulseren Demir Karakilic • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:07 UTC
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Parkinson's risk hunt: 2,200 volunteers help uncover hidden clues
Knowledge-focused CompletedThis completed study looked for genetic and environmental factors that increase the risk of developing Parkinson's disease. Researchers compared DNA and lifestyle data from over 2,200 people, including Parkinson's patients, people with related brain diseases, and healthy voluntee…
Matched conditions: RESTLESS LEGS SYNDROME
Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC