POST-POLYCYTHEMIA VERA MYELOFIBROSIS
Clinical trials for POST-POLYCYTHEMIA VERA MYELOFIBROSIS explained in plain language.
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New combo therapy aims to shrink spleen and ease symptoms in hard-to-treat myelofibrosis
Disease control TerminatedThis study tested whether adding the experimental drug parsaclisib to the standard drug ruxolitinib helps people with myelofibrosis whose spleen and symptoms haven't improved enough on ruxolitinib alone. The main goal was to see if the combination could shrink the spleen by at le…
Matched conditions: POST-POLYCYTHEMIA VERA MYELOFIBROSIS
Phase: PHASE3 • Sponsor: Incyte Corporation • Aim: Disease control
Last updated Jun 16, 2026 23:06 UTC
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New hope for myelofibrosis patients who failed standard therapy?
Disease control TerminatedThis study tested a drug called selinexor in 17 people with a rare bone marrow cancer (myelofibrosis) that did not respond to or could not tolerate standard JAK inhibitor treatments. The main goal was to see if the drug could shrink an enlarged spleen by at least 35%. The trial w…
Matched conditions: POST-POLYCYTHEMIA VERA MYELOFIBROSIS
Phase: PHASE2 • Sponsor: University of Utah • Aim: Disease control
Last updated Jun 10, 2026 13:28 UTC
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Myelofibrosis drug combo trial halted Mid-Study
Disease control TerminatedThis study tested whether adding the drug parsaclisib to the standard treatment ruxolitinib could better shrink enlarged spleens and ease symptoms in people with myelofibrosis, a rare bone marrow cancer. The trial planned to enroll 252 adults with intermediate or high-risk diseas…
Matched conditions: POST-POLYCYTHEMIA VERA MYELOFIBROSIS
Phase: PHASE3 • Sponsor: Incyte Corporation • Aim: Disease control
Last updated Jun 09, 2026 12:08 UTC