POEMS SYNDROME
Clinical trials for POEMS SYNDROME explained in plain language.
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New drug cocktail aims to tame rare nerve and blood disorder
Disease control Recruiting nowThis phase 2 trial tests a combination of three drugs—carfilzomib, cyclophosphamide, and dexamethasone—in 20 people newly diagnosed with POEMS syndrome, a rare disorder affecting nerves and blood. The goal is to see if the regimen can reduce abnormal proteins and improve symptoms…
Matched conditions: POEMS SYNDROME
Phase: PHASE2 • Sponsor: Shanghai Changzheng Hospital • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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Scientists hunt for genetic clues behind rare blood disorders
Knowledge-focused Recruiting nowThis study looks at a specific gene (IGLV1-44) to understand why it causes two different diseases: AL amyloidosis and POEMS syndrome. Researchers will analyze blood and bone marrow samples from 100 adults with these conditions or multiple myeloma. The goal is to find genetic patt…
Matched conditions: POEMS SYNDROME
Sponsor: Fondazione IRCCS Policlinico San Matteo di Pavia • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Mayo clinic launches gut bacteria study for rare plasma cell disorders
Knowledge-focused Recruiting nowThis study looks at the gut microbiome (the bacteria living in the digestive system) of people with POEMS syndrome, multiple myeloma, MGUS, AL amyloidosis, and healthy household members. Participants provide stool samples at home using a collection kit. The goal is to understand …
Matched conditions: POEMS SYNDROME
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:07 UTC