PMMR/MSS
Clinical trials for PMMR/MSS explained in plain language.
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Can a 16-Hour fast supercharge immunotherapy against rectal cancer?
Disease control Not yet recruitingThis phase II trial is testing whether a 16-hour fast before each dose of the immunotherapy drug serplulimab, combined with chemotherapy, can improve outcomes for people with a common type of locally advanced rectal cancer. The approach aims to boost the immune system's ability t…
Matched conditions: PMMR/MSS
Phase 2 • Sponsor: Zhejiang University • Aim: Disease control
Last updated Sep 10, 2026 00:00 UTC
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New combo therapy aims to boost remission in tough rectal cancer
Disease control Not yet recruitingThis phase 2 trial tests a new approach for high-risk locally advanced rectal cancer. It combines a shorter course of radiation with chemotherapy (capecitabine and oxaliplatin) and an immunotherapy drug (serplulimab). The study will compare this combo to standard chemoradiation i…
Matched conditions: PMMR/MSS
Phase 2 • Sponsor: Fudan University • Aim: Disease control
Last updated Jun 27, 2026 12:07 UTC