PILON FRACTURE
Clinical trials for PILON FRACTURE explained in plain language.
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Could a simple injection after a broken ankle prevent arthritis?
Disease control Recruiting nowThis study tests whether injecting N-acetylcysteine (NAC), an antioxidant, into the ankle right after a severe pilon fracture can keep cartilage cells alive and reduce the chance of developing post-traumatic arthritis. Thirty adults with closed high-energy pilon fractures will re…
Matched conditions: PILON FRACTURE
Phase: PHASE4 • Sponsor: University of Missouri-Columbia • Aim: Disease control
Last updated Jun 27, 2026 12:25 UTC
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Which surgery is best for frail seniors with broken ankles? new study aims to find out
Disease control Recruiting nowThis study compares two types of surgery for unstable ankle fractures in frail adults aged 60 and older. One group gets ankle fusion (joining the bones together), and the other gets open reduction and internal fixation (using plates and screws to hold the bones in place). A secon…
Matched conditions: PILON FRACTURE
Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's • Aim: Disease control
Last updated Jun 27, 2026 09:00 UTC
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Wooden block breakthrough: simpler ankle rehab shows promise
Symptom relief Recruiting nowThis study tests whether a simple wooden block stretching routine can replace standard physical therapy for people recovering from ankle or pilon fracture surgery. About 30 adults aged 18-65 who had surgery for these fractures will be randomly assigned to either the wooden block …
Matched conditions: PILON FRACTURE
Phase: NA • Sponsor: University of Virginia • Aim: Symptom relief
Last updated Jun 27, 2026 13:04 UTC