PIK3CA-RELATED OVERGROWTH SPECTRUM
Clinical trials for PIK3CA-RELATED OVERGROWTH SPECTRUM explained in plain language.
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New hope for rare vascular malformations: targeted drugs enter trial
Disease control Recruiting nowThis phase 2 trial is testing two targeted drugs—alpelisib and mirdametinib—in 50 people with slow-flow or fast-flow vascular malformations that haven't responded to standard treatments. The goal is to see if these drugs can improve each person's most bothersome symptom over 48 w…
Matched conditions: PIK3CA-RELATED OVERGROWTH SPECTRUM
Phase: PHASE2 • Sponsor: Murdoch Childrens Research Institute • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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Scientists investigate rare overgrowth disorder proteus syndrome
Knowledge-focused Recruiting nowThis study aims to understand the genetic and biological causes of Proteus syndrome, a rare condition causing abnormal growth of bones, skin, and other tissues. Researchers will follow up to 1,500 participants over time, using medical exams, imaging, and blood tests to track how …
Matched conditions: PIK3CA-RELATED OVERGROWTH SPECTRUM
Sponsor: National Human Genome Research Institute (NHGRI) • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:02 UTC