PI3K GENE MUTATION
Clinical trials for PI3K GENE MUTATION explained in plain language.
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New precision drug targets Hard-to-Treat cancers in early human trial
Disease control Recruiting nowThis study tests a new drug called OKI-219 in people with advanced solid tumors or breast cancer that have a specific change in the PI3K gene. The trial has two parts: first, finding the safest dose of OKI-219 alone, then testing it in combination with other cancer drugs. About 2…
Matched conditions: PI3K GENE MUTATION
Phase: PHASE1 • Sponsor: OnKure, Inc. • Aim: Disease control
Last updated Apr 29, 2026 05:31 UTC
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New hope for rare blood vessel disorders: targeted drugs enter trial
Disease control Recruiting nowThis study tests two targeted drugs for people with vascular malformations (abnormal blood or lymph vessels). It includes 50 participants aged 2 and older. One group with slow-flow malformations and a specific gene mutation receives alpelisib for 48 weeks. Another group with fast…
Matched conditions: PI3K GENE MUTATION
Phase: PHASE2 • Sponsor: Murdoch Childrens Research Institute • Aim: Disease control
Last updated Apr 29, 2026 05:30 UTC