PI3K GENE MUTATION
Clinical trials for PI3K GENE MUTATION explained in plain language.
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New precision drug targets Hard-to-Treat cancers in early trial
Disease control Recruiting nowThis early-stage study tests a new drug, OKI-219, designed to attack cancer cells with a specific mutation (PI3KαH1047R). About 200 adults with advanced solid tumors or breast cancer will receive the drug alone or with other treatments. The goal is to find safe doses and see if t…
Matched conditions: PI3K GENE MUTATION
Phase: PHASE1 • Sponsor: OnKure, Inc. • Aim: Disease control
Last updated Jun 08, 2026 13:05 UTC
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New hope for rare blood vessel disorders: targeted drugs enter trial
Disease control Recruiting nowThis study tests two targeted drugs for people with vascular malformations (abnormal blood or lymph vessels). Participants with slow-flow malformations and a specific gene mutation receive alpelisib, while those with fast-flow malformations and another mutation receive mirdametin…
Matched conditions: PI3K GENE MUTATION
Phase: PHASE2 • Sponsor: Murdoch Childrens Research Institute • Aim: Disease control
Last updated May 19, 2026 12:00 UTC