OPIOID CRAVING
Clinical trials for OPIOID CRAVING explained in plain language.
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Could buspirone and lofexidine take the edge off opioid withdrawal?
Symptom relief Recruiting nowThis Phase 2 trial tests whether adding buspirone (an anxiety medication) to lofexidine (a withdrawal drug) can reduce opioid withdrawal symptoms and cravings during detox. About 100 adults with opioid use disorder will stay in a residential setting for 10–12 days, undergo a step…
Matched conditions: OPIOID CRAVING
Phase: PHASE2 • Sponsor: University of Maryland, Baltimore • Aim: Symptom relief
Last updated Jul 30, 2026 00:00 UTC
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Scientists study why opioid withdrawal hits some harder than others
Knowledge-focused Recruiting nowThis study looks at how opioid withdrawal symptoms vary from person to person. Sixty adults with opioid use disorder will go through a medically supervised taper using hydromorphone and lofexidine. Researchers will measure withdrawal severity during the taper and after a naloxone…
Matched conditions: OPIOID CRAVING
Phase: PHASE2 • Sponsor: University of Maryland, Baltimore • Aim: Knowledge-focused
Last updated Jun 26, 2026 15:36 UTC