NUTRITIONAL AND METABOLIC DISEASES

This study tests two experimental drugs, PF-08653945 and PF-08653944, given alone or together, to see if they help adults with overweight or obesity lose weight safely. About 872 participants will receive either the drugs or a placebo. The main goal is to measure how much body we…

This study is testing whether a special chewing gum containing galactooligosaccharides (GOS) can help overweight adults lose weight and improve their metabolism. Researchers will measure changes in body mass index (BMI), blood pressure, and gut bacteria over time. The study aims …

This pilot study tests whether a 12-week family-centered whole foods diet (without calorie counting) can help prevent type 2 diabetes in adults with prediabetes and improve eating habits for both adults and children. About 30 adult-child pairs will participate, with half receivin…

This study looks at how eating more carbohydrates or fats changes blood fat levels and liver health in 60 healthy adults. Researchers will also check if a person's genes affect these responses. The goal is to learn which diet might lower the risk of heart disease and diabetes.

This study looks at why many people with Parkinson's disease crave sugary foods and how those sugars affect their body and symptoms. Researchers will give 50 participants a sugary drink and a placebo drink on different days to measure changes in insulin, blood sugar, and movement…