NMOSD
Clinical trials for NMOSD explained in plain language.
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Major trial to determine best drug for rare autoimmune disease
Disease control Not yet recruitingThis study compares five FDA-approved drugs—rituximab, ravulizumab, inebilizumab, satralizumab, and eculizumab—to see which best prevents relapses in people with neuromyelitis optica spectrum disorder (NMOSD), a rare autoimmune condition that can cause vision loss and paralysis. …
Matched conditions: NMOSD
Phase: PHASE4 • Sponsor: Massachusetts General Hospital • Aim: Disease control
Last updated Jun 27, 2026 14:03 UTC
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New hope for NMOSD patients: drug aims to slash relapse rate
Disease control Not yet recruitingThis study tests a drug called ravulizumab in about 19 Chinese adults with a rare autoimmune disease called NMOSD. The goal is to see if it can reduce the number of disease attacks (relapses) and slow disability. Participants must have had at least one attack in the past year and…
Matched conditions: NMOSD
Phase: PHASE3 • Sponsor: Alexion Pharmaceuticals, Inc. • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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New antibody treatment could tame rare brain disease Flare-Ups
Disease control Not yet recruitingThis study tests whether monoclonal antibodies can safely and effectively treat acute attacks of neuromyelitis optica spectrum disorder (NMOSD), a rare disease that causes inflammation in the eyes and spinal cord. Researchers will enroll 40 adults experiencing a recent flare-up a…
Matched conditions: NMOSD
Sponsor: First Affiliated Hospital of Chongqing Medical University • Aim: Disease control
Last updated Jun 26, 2026 19:21 UTC
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Hormone clues sought in rare nerve disease
Knowledge-focused Not yet recruitingThis study will measure sex hormone levels in 4000 people with NMOSD, a rare autoimmune disease affecting the nerves. Researchers want to see if hormone changes are linked to the disease. Participants will give blood samples for hormone testing. The study does not test any new dr…
Matched conditions: NMOSD
Sponsor: Xiamen Hospital of Traditional Chinese Medicine • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC