NEOPLASMS, COLORECTAL
Clinical trials for NEOPLASMS, COLORECTAL explained in plain language.
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New drug combo targets hard-to-treat KRAS-mutant cancers
Disease control OngoingThis study tests a new drug called JDQ443, alone or with other treatments, in people with advanced solid tumors that have a specific KRAS G12C mutation. The goal is to find safe doses and see if the drug shrinks tumors. About 74 adults with lung or colorectal cancer that has not …
Matched conditions: NEOPLASMS, COLORECTAL
Phase: PHASE1, PHASE2 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated Jun 15, 2026 19:06 UTC
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New pill targets aggressive tumors with genetic flaw
Disease control OngoingThis early-phase study tests an experimental oral drug (GSK4418959) in adults with advanced solid tumors that have specific genetic changes (dMMR or MSI-H). The drug works by blocking a protein (WRN) that these tumors need to survive. The study aims to see if the drug, alone or w…
Matched conditions: NEOPLASMS, COLORECTAL
Phase: PHASE1, PHASE2 • Sponsor: GlaxoSmithKline • Aim: Disease control
Last updated Jun 10, 2026 13:24 UTC
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New drug offers hope for Hard-to-Treat cancers
Disease control OngoingThis study tests a new drug called 9-ING-41, which targets a protein (GSK-3β) that helps cancer grow. It is for adults with advanced cancers that have not responded to standard treatments. The drug is given alone or with chemotherapy to see if it is safe and helps shrink tumors o…
Matched conditions: NEOPLASMS, COLORECTAL
Phase: PHASE2 • Sponsor: Actuate Therapeutics Inc. • Aim: Disease control
Last updated Jun 03, 2026 12:05 UTC