MUTATION
Clinical trials for MUTATION explained in plain language.
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Beyond BRCA: new gene panel could sharpen cancer risk prediction
Knowledge-focused OngoingThis study is investigating whether testing for a panel of 24 genes, in addition to the well-known BRCA1 and BRCA2 genes, can better estimate the risk of breast and ovarian cancer. Researchers will analyze genetic samples from people with a family history of these cancers, as wel…
Matched conditions: MUTATION
Phase: NA • Sponsor: UNICANCER • Aim: Knowledge-focused
Last updated Aug 02, 2026 00:00 UTC
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Gene study aims to solve wolfram syndrome mystery
Knowledge-focused OngoingThis study looks at 45 people with certain changes in the WFS1 gene to figure out if they have a milder, dominant form of wolfram-like syndrome instead of the more severe recessive form. Researchers will use eye scans (OCT) to see if the gene changes are linked to specific eye pr…
Matched conditions: MUTATION
Sponsor: Hôpital Necker-Enfants Malades • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:03 UTC
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Deep dive into DNA: new study hunts for hidden hereditary cancer clues
Knowledge-focused OngoingThis study looks at the complete DNA and RNA of 10 people and their families who are at high risk for hereditary cancer but have no known genetic cause. Researchers will use whole genome sequencing and tumor analysis to discover new genetic changes that may lead to cancer. The go…
Matched conditions: MUTATION
Sponsor: University Health Network, Toronto • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC