MUSCLE-INVASIVE UROTHELIAL CARCINOMA OF THE BLADDER
Clinical trials for MUSCLE-INVASIVE UROTHELIAL CARCINOMA OF THE BLADDER explained in plain language.
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Experimental combo shows promise for Tough-to-Treat cancers
Disease control OngoingThis phase II trial is testing a combination of two drugs—sEphB4-HSA and pembrolizumab (Keytruda)—in 70 people with advanced bladder or prostate cancers that have not responded to standard treatments. The goal is to see if the combo is safe and can shrink tumors. Participants rec…
Matched conditions: MUSCLE-INVASIVE UROTHELIAL CARCINOMA OF THE BLADDER
Phase: PHASE2 • Sponsor: University of Southern California • Aim: Disease control
Last updated Jun 27, 2026 13:04 UTC
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Bladder cancer patients may skip surgery with new drug combo
Disease control OngoingThis phase 3 trial tests a new approach for people with muscle-invasive bladder cancer who cannot or choose not to have their bladder removed. Participants receive either a combination of TAR-200 (a drug placed directly into the bladder) plus cetrelimab (an immunotherapy), or sta…
Matched conditions: MUSCLE-INVASIVE UROTHELIAL CARCINOMA OF THE BLADDER
Phase: PHASE3 • Sponsor: Janssen Research & Development, LLC • Aim: Disease control
Last updated Jun 27, 2026 13:04 UTC
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New hope for bladder cancer patients who can't take chemo
Disease control OngoingThis study tests two immunotherapy drugs (nivolumab with or without urelumab) given before bladder removal surgery in 15 patients with muscle-invasive bladder cancer who cannot or refuse standard chemotherapy. The goal is to see if adding urelumab boosts the immune response again…
Matched conditions: MUSCLE-INVASIVE UROTHELIAL CARCINOMA OF THE BLADDER
Phase: PHASE2 • Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins • Aim: Disease control
Last updated Jun 27, 2026 12:04 UTC