MULTIPLE SCLEROSIS (MS)
Clinical trials for MULTIPLE SCLEROSIS (MS) explained in plain language.
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CAR-T therapy targets autoimmune diseases, but trial never started
Disease control TerminatedThis study planned to test a new CAR-T cell therapy called LCAR-AIO in adults with relapsed or treatment-resistant neurological autoimmune diseases, including multiple sclerosis and myasthenia gravis. The goal was to check safety and find the right dose. However, the trial was wi…
Matched conditions: MULTIPLE SCLEROSIS (MS)
Phase: PHASE1 • Sponsor: Union Hospital, Tongji Medical College, Huazhong University of Science and Technology • Aim: Disease control
Last updated Jun 27, 2026 14:02 UTC
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New hope for kids with MS: drug showdown begins
Disease control OngoingThis study tests two newer multiple sclerosis drugs, ofatumumab and siponimod, against an older one, fingolimod, in 129 children aged 10 to 17. The goal is to see if the newer drugs are at least as good at preventing MS relapses. Participants take one of the three drugs for two y…
Matched conditions: MULTIPLE SCLEROSIS (MS)
Phase: PHASE3 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated Jun 27, 2026 12:33 UTC
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MS drug use in pregnancy under the microscope: is it safe for baby?
Knowledge-focused OngoingThis study looks at how many women with multiple sclerosis (MS) use the drug interferon-beta during the second and third trimesters of pregnancy in Finland and Sweden. Researchers want to know if there are enough cases to study whether the drug affects pregnancy outcomes like bir…
Matched conditions: MULTIPLE SCLEROSIS (MS)
Sponsor: Bayer • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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French study tracks daily life changes in MS patients on newer drug
Knowledge-focused OngoingThis study follows 302 adults with multiple sclerosis in France who are starting the drug ofatumumab as part of their normal care. Researchers will measure how patients' quality of life changes after 12 months using a special questionnaire. The goal is to understand real-world be…
Matched conditions: MULTIPLE SCLEROSIS (MS)
Sponsor: Novartis Pharmaceuticals • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:24 UTC