MITRAL STENOSIS

This study tests a new device (TS-RF system) that uses radiofrequency energy to help doctors safely reach the left side of the heart during procedures for abnormal heart rhythms or mitral stenosis. About 70 adults will be randomly assigned to receive either the new device or a st…

This study tests a new device called the Cephea Mitral Valve System for people with a leaky or narrowed mitral heart valve. The goal is to see if it is safe and works well for patients who are not good candidates for open-heart surgery. About 50 people will get the device and be …

This study is testing a new device called the Cephea Mitral Valve System for people with mitral valve disease (leaky or narrowed heart valves) who cannot have open-heart surgery. The goal is to see if the device is safe and works well. About 20 people will take part.

This study is testing a new way to replace a damaged heart valve (the mitral valve) without open-heart surgery. It uses a special valve delivered through a thin tube (catheter) for people with severe symptoms who are not healthy enough for standard surgery. The study will enroll …

This study tests a new device (Intrepid TMVR) to replace the mitral valve in people with severe mitral regurgitation (leaky heart valve) who are not candidates for standard surgery or repair. About 400 participants will receive the device and be followed for safety and effectiven…

This study tests whether a portable electronic stethoscope, combined with machine learning, can accurately detect valvular heart disease. About 125 people with and without the condition will use the device and also receive standard heart tests. Researchers will compare the device…

This study is a registry that collects information from 1,000 people with symptomatic mitral valve disease, including mitral regurgitation and stenosis. The goal is to better understand how correcting these heart valve problems with a less invasive procedure called transcatheter …

This study compares people who have had a mitral valve procedure for mitral stenosis with healthy volunteers. Researchers will measure exercise capacity, muscle oxygen levels, and artery stiffness to understand long-term effects. The goal is to gather knowledge that may improve f…

This observational study will follow 400 patients with mitral stenosis who undergo a procedure called percutaneous mitral balloon commissurotomy (PMBC), where a balloon is used to open a narrowed heart valve. Researchers want to see how patients fare afterward and find the best w…