MITRAL STENOSIS

This study is for people with a severely hardened mitral valve (mitral annular calcification) that causes symptoms like shortness of breath and fatigue, but who are too high-risk for open-heart surgery. The trial will test a new way to replace the valve using a thin tube inserted…

This study is testing a new device called the Cephea Mitral Valve System to treat people with mitral valve disease (leaky or narrowed heart valves) who are not good candidates for open-heart surgery. The device is placed using a thin tube through a blood vessel, avoiding major su…

This study follows 400 people with mitral stenosis who are getting a balloon procedure to open their heart valve. Researchers want to see how well the treatment works and find the best balloon size to use. The goal is to improve care for future patients.

This study is a registry that collects information from 1,000 people with symptomatic mitral valve disease (leaky or narrowed heart valve). The goal is to learn how patients respond to a less-invasive valve replacement procedure called TMVR. This data will help doctors improve tr…

This study looks at how well people who have had treatment for mitral stenosis (a narrowed heart valve) can exercise compared to healthy people. Researchers will measure exercise capacity, muscle oxygen levels, and artery stiffness. The goal is to better understand long-term reco…