MICROSATELLITE INSTABILITY HIGH
Clinical trials for MICROSATELLITE INSTABILITY HIGH explained in plain language.
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Can a new drug combo revive Immunotherapy's power against resistant tumors?
Disease control TerminatedThis trial is testing whether an experimental drug called NC410, when combined with the immunotherapy drug pembrolizumab, can safely and effectively treat people with advanced solid tumors that have not responded to standard immunotherapy or that are unlikely to respond. The stud…
Matched conditions: MICROSATELLITE INSTABILITY HIGH
Phase: PHASE1, PHASE2 • Sponsor: NextCure, Inc. • Aim: Disease control
Last updated Aug 15, 2026 00:00 UTC
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Experimental cancer combo shows early promise but study halted
Disease control TerminatedThis early-phase trial tested a new drug called nanrilkefusp alfa, which helps activate immune cells, both alone and combined with the immunotherapy pembrolizumab. It included 115 people with various advanced solid tumors that had stopped responding to standard treatments. The st…
Matched conditions: MICROSATELLITE INSTABILITY HIGH
Phase: PHASE1 • Sponsor: SOTIO Biotech AG • Aim: Disease control
Last updated Jun 27, 2026 12:01 UTC