LYMPHATIC MALFORMATIONS
Clinical trials for LYMPHATIC MALFORMATIONS explained in plain language.
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New drug targets root cause of rare overgrowth diseases in kids and adults
Disease control Recruiting nowThis study tests a new drug, RLY-2608, designed to block a faulty protein that causes abnormal growth in people with PIK3CA-related overgrowth spectrum (PROS) and related malformations. The trial enrolls 277 adults and children to see if the drug can safely shrink overgrown tissu…
Matched conditions: LYMPHATIC MALFORMATIONS
Phase: PHASE2 • Sponsor: Relay Therapeutics, Inc. • Aim: Disease control
Last updated May 15, 2026 11:55 UTC
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New drug shrinks Fluid-Filled growths in Gene-Linked disorder?
Disease control Recruiting nowThis study tests whether alpelisib, a drug that targets a specific gene mutation (PIK3CA), can shrink lymphatic malformations—abnormal fluid-filled growths—and improve symptoms in children and adults. About 232 participants will receive either alpelisib or a placebo, and doctors …
Matched conditions: LYMPHATIC MALFORMATIONS
Phase: PHASE2, PHASE3 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated May 14, 2026 12:03 UTC