LOCALLY ADVANCED HEAD AND NECK SQUAMOUS CELL CARCINOMA
Clinical trials for LOCALLY ADVANCED HEAD AND NECK SQUAMOUS CELL CARCINOMA explained in plain language.
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New combo therapy targets tough head and neck cancers
Disease control CompletedThis phase 2 study tested a combination of the drug Tarceva (erlotinib) with RADPLAT (radiation and intra-arterial cisplatin) in 21 patients with advanced head and neck cancer. The goal was to see if the combination was safe and effective at shrinking tumors. Researchers measured…
Matched conditions: LOCALLY ADVANCED HEAD AND NECK SQUAMOUS CELL CARCINOMA
Phase: PHASE2 • Sponsor: Southern Illinois University • Aim: Disease control
Last updated Jun 27, 2026 13:05 UTC
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New chemo combo shows promise for head and neck cancer before surgery
Disease control CompletedThis phase 2 trial tested two chemotherapy drugs, paclitaxel and carboplatin, given before surgery to 79 people with locally advanced head and neck cancer. The goal was to see how well the drugs shrink tumors before surgery. The main measure was a major pathologic response, meani…
Matched conditions: LOCALLY ADVANCED HEAD AND NECK SQUAMOUS CELL CARCINOMA
Phase: PHASE2 • Sponsor: Yonsei University • Aim: Disease control
Last updated Jun 27, 2026 12:38 UTC
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Immunotherapy combo shows promise in head and neck cancer trial
Disease control CompletedThis large Phase 3 trial tested whether adding the immunotherapy drug pembrolizumab (Keytruda) to standard chemoradiation helps people with locally advanced head and neck cancer live longer without the disease getting worse. Over 800 participants received either pembrolizumab plu…
Matched conditions: LOCALLY ADVANCED HEAD AND NECK SQUAMOUS CELL CARCINOMA
Phase: PHASE3 • Sponsor: Merck Sharp & Dohme LLC • Aim: Disease control
Last updated Jun 27, 2026 09:01 UTC
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New combo therapy shows promise for tough head and neck cancers
Disease control CompletedThis phase 2 trial tested a combination of a short, intense course of radiation (quad-shot) and the immunotherapy drug pembrolizumab in 21 people with advanced, recurrent, or metastatic head and neck cancer. The goal was to see if the combination could shrink tumors and be safe. …
Matched conditions: LOCALLY ADVANCED HEAD AND NECK SQUAMOUS CELL CARCINOMA
Phase: PHASE2 • Sponsor: Wake Forest University Health Sciences • Aim: Disease control
Last updated Jun 27, 2026 07:58 UTC
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Lifting weights, lifting spirits: exercise eases chemo side effects
Symptom relief CompletedThis study looked at whether a group resistance exercise program could help head and neck cancer patients maintain muscle and quality of life during chemoradiation. Twenty adults with advanced head and neck cancer took part in supervised strength training sessions. Researchers me…
Matched conditions: LOCALLY ADVANCED HEAD AND NECK SQUAMOUS CELL CARCINOMA
Phase: NA • Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Symptom relief
Last updated Jun 27, 2026 13:02 UTC