HOMOZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA (HOFH)
Clinical trials for HOMOZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA (HOFH) explained in plain language.
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New injection aims to tame Ultra-High cholesterol in rare genetic disorder
Disease control Recruiting nowThis study is testing an investigational injection called EDP167 in adults with a rare, severe genetic condition that causes extremely high cholesterol from birth. The goal is to see if the injections can safely lower 'bad' cholesterol (LDL-C) levels over 24 weeks. Participants w…
Matched conditions: HOMOZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA (HOFH)
Phase: PHASE2 • Sponsor: Eddingpharm (Zhuhai) Co., Ltd. • Aim: Disease control
Last updated Apr 01, 2026 23:26 UTC
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CRISPR One-Shot aims to fix stubborn cholesterol for good
Disease control Recruiting nowThis is the first human trial of an experimental one-time treatment called CTX310, which uses CRISPR gene-editing technology. It aims to permanently lower harmful cholesterol and fat levels in the blood of adults whose levels don't respond well to existing medications. The study …
Matched conditions: HOMOZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA (HOFH)
Phase: PHASE1 • Sponsor: CRISPR Therapeutics AG • Aim: Disease control
Last updated Mar 25, 2026 14:07 UTC
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Catching a silent killer at birth: new study hunts for inherited heart risk in babies
Diagnosis Recruiting nowThis study aims to find babies born with a genetic condition that causes very high cholesterol, called familial hypercholesterolemia (FH). Researchers will work with expecting parents who have FH to test their newborns with cheek swabs and small blood samples. The goal is to iden…
Matched conditions: HOMOZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA (HOFH)
Phase: NA • Sponsor: University of Wisconsin, Madison • Aim: Diagnosis
Last updated Mar 31, 2026 12:11 UTC