HEALTHY ADULT SUBJECTS

This study looked at how a medicine called ADL-018 behaves in the body when given by two different devices: an autoinjector (like an EpiPen) and a regular syringe. 150 healthy adults received a single dose under the skin. The goal was to see if the two methods deliver the drug si…

This study tested a single dose of SIM0718 injection in 178 healthy adults in China to see how the drug moves through the body, how safe it is, and whether it triggers an immune response. Participants were healthy men and women aged 18 to 50. The goal was to gather basic informat…

This study tested whether a new tablet form of edaravone (TTYP01) works similarly to the existing injection and oral suspension forms in healthy adults. 29 participants took each form in a random order under fasting conditions. The goal was to compare how the drug is absorbed and…

This study looked at how the drug edaravone enters the bloodstream when given as a liquid by mouth or through a nasogastric tube. Thirty-six healthy Japanese adults took a single dose in a crossover design. The goal was to see if both methods deliver the drug similarly and to che…

This study looked at how eating different types of meals changes the way the body absorbs and processes an oral form of edaravone. Sixteen healthy Japanese adults took the drug under various meal conditions, including fasting. The goal was to gather information, not to treat any …

This early-stage study tested an oral version of edaravone in 74 healthy adult men to see how the body processes it and if it is safe. Participants took single or multiple doses of the drug as a solution or suspension. The goal was to gather information on side effects and drug l…

This early-stage study looked at how an oral form of edaravone interacts with other common drugs and how it behaves in the body. It involved 84 healthy adult Japanese and Caucasian men. The goal was to gather safety and drug interaction data, not to treat any disease.

This study tested whether an oral liquid version of edaravone works the same as the intravenous (IV) version in 42 healthy Japanese adults aged 20 to 45. Participants received a single dose of each form, and researchers measured drug levels in the blood to compare absorption. The…

This study tested whether MCI-186, an experimental drug, changes the heart's electrical activity (QT interval) in 27 healthy adult men. Participants received a low dose, a high dose, and a placebo on separate days. The goal was to see if the drug causes heart rhythm issues, helpi…