GLIOBLASTOMA, IDH-WILDTYPE
Clinical trials for GLIOBLASTOMA, IDH-WILDTYPE explained in plain language.
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New drug combo tested in fight against deadly brain cancer
Disease control TerminatedThis study is testing a new two-part treatment for aggressive brain tumors that have returned or worsened. It aims to see if giving the drugs GI-102 and pembrolizumab just before surgery is safe and can help the immune system attack the tumor. The trial is for adults with specifi…
Matched conditions: GLIOBLASTOMA, IDH-WILDTYPE
Phase: PHASE2 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated Mar 31, 2026 12:12 UTC
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Repurposed transplant drug enters fight against deadly brain cancer
Disease control OngoingThis early-stage trial is testing whether adding a drug called mycophenolate mofetil (MMF) to standard glioblastoma treatment is safe and might make the cancer more sensitive to chemotherapy. MMF is an immunosuppressant commonly used to prevent organ rejection after transplants. …
Matched conditions: GLIOBLASTOMA, IDH-WILDTYPE
Phase: PHASE1 • Sponsor: Northwestern University • Aim: Disease control
Last updated Mar 30, 2026 14:29 UTC
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New hope: immune therapy targets aggressive recurrent brain tumors
Disease control OngoingThis study tests whether two immunotherapy drugs (ipilimumab and nivolumab) can help control recurrent, aggressive brain tumors that have many genetic mutations. The treatment aims to help the body's immune system recognize and attack the cancer cells. Researchers are measuring w…
Matched conditions: GLIOBLASTOMA, IDH-WILDTYPE
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 27, 2026 12:40 UTC
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New pill aims to target and shrink tough brain cancers
Disease control OngoingThis is a first-in-human study to find a safe dose of an experimental pill called WSD0922-FU for people with aggressive brain tumors or lung cancer that has spread to the brain. The pill is designed to block a specific protein (EGFR) that drives these cancers and may be able to r…
Matched conditions: GLIOBLASTOMA, IDH-WILDTYPE
Phase: PHASE1 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated Mar 27, 2026 12:39 UTC