FUNGAL INFECTION

This study tested a gel called CGB-400 on 15 adults with toenail fungus. The goal was to see if the gel could clear the fungus and improve how the nails look. Participants applied the gel for up to 12 weeks, and doctors checked their nails at several visits.

This study tested a new drug called rezafungin to prevent serious fungal infections in 602 adults receiving a bone marrow transplant. Participants received either rezafungin or the standard antifungal treatment. The goal was to see if rezafungin is safer and more effective at kee…

This early-stage study tested a new oral drug called APX001 in 46 healthy volunteers to see if it is safe and how the body handles it. Some participants received the drug and others received a placebo (a dummy pill). The study also looked at how food affects the drug and whether …

This study looked at whether measuring certain markers of fungal infection in the blood could help doctors decide to stop antifungal drugs earlier in critically ill patients. The goal was to reduce the number of days patients receive these medications without increasing risk. The…

This study tracked 219 adults with severe COVID-19 who needed a ventilator to breathe. Researchers wanted to see how many also developed serious fungal infections, especially a lung infection called aspergillosis. They used standard tests to check for fungi, but did not give any …

This early-stage study tested the safety and tolerability of a new antifungal drug called APX001 in 200 healthy adults. Participants received either the drug or a placebo by IV infusion, and researchers monitored for side effects and how the drug moved through the body. The goal …