FUNGAL INFECTION

This study tested whether using special fungal markers (biomarkers) could help doctors safely stop antifungal drugs earlier in ICU patients. The goal was to reduce the length of treatment and avoid unnecessary side effects. The study included 110 critically ill adults who needed …

This study tested a special gel, CGB-400, on 15 adults with toenail fungus. The goal was to see if the gel could clear the fungus and make the nails look better. Participants applied the gel for 12 weeks, with follow-up visits to check progress.

This early-stage trial tested the safety and tolerability of a new antifungal drug called APX001 in 200 healthy volunteers. Participants received either single or multiple doses of the drug or a placebo. The study focused on side effects and how the drug moves through the body, n…

This study tested a new medicine called rezafungin to see if it can prevent serious fungal infections in adults getting a bone marrow transplant. About 600 participants received either rezafungin or the standard treatment. The goal was to see if rezafungin helps more people stay …

This study monitored 219 adults with severe COVID-19 who needed a ventilator for at least 72 hours. Researchers checked for serious fungal infections, especially aspergillosis, using standard diagnostic methods. The goal was to learn how common these infections are and what puts …

This Phase 1 trial tested the safety and tolerability of a new antifungal drug called APX001 in 46 healthy volunteers. Researchers gave single and multiple doses, both orally and intravenously, to see how the body handles the drug and whether food affects it. The study also looke…