EXTENSIVE STAGE SMALL CELL LUNG CARCINOMA
Clinical trials for EXTENSIVE STAGE SMALL CELL LUNG CARCINOMA explained in plain language.
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Lung cancer trial tests two new combo therapies against tough disease
Disease control CompletedThis phase II trial studied 168 people with extensive-stage small cell lung cancer. Researchers added either vismodegib or cixutumumab to standard chemotherapy (cisplatin and etoposide) to see if these combinations worked better than chemo alone. The goal was to slow cancer growt…
Matched conditions: EXTENSIVE STAGE SMALL CELL LUNG CARCINOMA
Phase: PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 27, 2026 14:03 UTC
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Could a PARP inhibitor boost chemo for tough lung cancer?
Disease control CompletedThis study tested whether adding veliparib (a PARP inhibitor) to standard chemotherapy (cisplatin and etoposide) helps people with extensive stage small cell lung cancer or certain other lung cancers that have spread. In the first phase, researchers found the best dose of velipar…
Matched conditions: EXTENSIVE STAGE SMALL CELL LUNG CARCINOMA
Phase: PHASE1, PHASE2 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Jun 27, 2026 14:02 UTC
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New radiation technique aims to protect memory in lung cancer patients
Disease control CompletedThis study tested whether avoiding the hippocampus during whole-brain radiation could reduce memory side effects in people with small cell lung cancer. Over 400 patients received either standard whole-brain radiation or a version that spares the hippocampus. The goal was to see i…
Matched conditions: EXTENSIVE STAGE SMALL CELL LUNG CARCINOMA
Phase: PHASE2, PHASE3 • Sponsor: NRG Oncology • Aim: Disease control
Last updated Jun 27, 2026 12:36 UTC
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Immunotherapy-Radiation combo shows promise in tough lung cancer
Disease control CompletedThis early-phase trial tested the safety and best dose of the immunotherapy drug pembrolizumab when combined with chemotherapy and radiation for people with small cell lung cancer. The goal was to see if adding pembrolizumab helps the immune system fight the cancer more effective…
Matched conditions: EXTENSIVE STAGE SMALL CELL LUNG CARCINOMA
Phase: PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Jun 27, 2026 11:00 UTC
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Old arthritis drug paired with immune suppressant shows promise against tough lung cancers
Disease control CompletedThis study tested two drugs—auranofin (originally for arthritis) and sirolimus (an immune suppressant)—in 29 people with advanced or recurrent lung cancer who had no standard options left. The goal was to find the safest dose and see if the combination could slow cancer growth. T…
Matched conditions: EXTENSIVE STAGE SMALL CELL LUNG CARCINOMA
Phase: PHASE1, PHASE2 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated Jun 26, 2026 13:58 UTC