ESCC
Clinical trials for ESCC explained in plain language.
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New drug duo aims to shrink esophageal tumors before surgery
Disease control Recruiting nowThis study tests whether giving two drugs (anlotinib and bemocizumab) before surgery can improve outcomes for people with a type of esophageal cancer. About 25 adults with stage II-IIIB esophageal squamous cell carcinoma will receive the combination, then have surgery. The goal i…
Matched conditions: ESCC
Phase: NA • Sponsor: Nanfang Hospital, Southern Medical University • Aim: Disease control
Last updated Jun 15, 2026 19:05 UTC
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New targeted therapy ALX2004 enters first human trials for tough cancers
Disease control Recruiting nowThis early-phase study tests a new drug called ALX2004 in about 170 people with advanced or metastatic solid tumors (lung, head and neck, colorectal, or esophageal cancer) that have not responded to standard treatments. ALX2004 is an antibody-drug conjugate designed to deliver a …
Matched conditions: ESCC
Phase: PHASE1 • Sponsor: ALX Oncology Inc. • Aim: Disease control
Last updated Jun 15, 2026 18:57 UTC
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New hope for advanced cancers? JAB-8263 enters human testing
Disease control Recruiting nowThis study tests a new drug called JAB-8263 in adults with advanced solid tumors or blood cancers that have stopped responding to standard treatments. The goal is to find a safe dose and see if the drug can shrink tumors. About 152 people will take part in this early-phase trial.
Matched conditions: ESCC
Phase: PHASE1, PHASE2 • Sponsor: Jacobio Pharmaceuticals Co., Ltd. • Aim: Disease control
Last updated Jun 15, 2026 18:57 UTC
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New drug NRM-823 takes on Hard-to-Treat cancers
Disease control Recruiting nowThis early-stage study tests a new drug, NRM-823, alone or with an immunotherapy, in people with advanced solid tumors that have not responded to other treatments. The main goals are to check safety and find the right dose. About 150 adults with cancers like lung, ovarian, or tri…
Matched conditions: ESCC
Phase: PHASE1 • Sponsor: Normunity AccelCo, Inc. • Aim: Disease control
Last updated Jun 11, 2026 11:57 UTC
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New combo therapy before surgery shows promise for tough esophageal cancer
Disease control Recruiting nowThis study tests a new approach for people with locally advanced esophageal cancer. Participants first receive a combination of immunotherapy and chemotherapy, then chemoradiation, followed by surgery. The goal is to see if this sequence can shrink tumors more effectively and imp…
Matched conditions: ESCC
Phase: PHASE2 • Sponsor: National Taiwan University Hospital • Aim: Disease control
Last updated Jun 10, 2026 13:26 UTC
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Simple blood test could spot deadly esophageal cancer sooner
Diagnosis Recruiting nowThis study is developing a new blood test to find esophageal cancer at an early, more treatable stage. Researchers will analyze tiny particles in the blood of 600 adults with and without the disease. The goal is to create a simple, non-invasive screening tool that could replace u…
Matched conditions: ESCC
Sponsor: City of Hope Medical Center • Aim: Diagnosis
Last updated Jun 03, 2026 12:07 UTC