DRUG-RESISTANT PARTIAL EPILEPSY

This study tested whether a single dose of naloxone, given right after a generalized tonic-clonic seizure, can help people with epilepsy breathe better and avoid sudden death. Researchers enrolled 485 adults with drug-resistant epilepsy who were already in the hospital for monito…

This study tested whether a special type of MRI that measures sodium levels in the brain can help locate the exact area causing seizures in people with drug-resistant epilepsy. 78 patients who were already scheduled for epilepsy surgery received a sodium MRI scan. Researchers com…

This study tested whether special microelectrodes can record 'fast ripples'—tiny brain signals that may help locate where seizures start. 54 adults with drug-resistant epilepsy who needed brain monitoring for surgery planning took part. The goal was to see if these electrodes cou…

This completed study enrolled over 1,000 people with drug-resistant partial epilepsy to see if severe drops in oxygen levels during seizures can predict later sudden unexpected death (SUDEP). Participants had their seizures recorded with video-EEG monitoring. The goal is to bette…

This study involved 47 people with drug-resistant epilepsy and healthy volunteers. Researchers recorded brain activity simultaneously using implanted electrodes (intracranial EEG) and non-invasive scans (MEG or fMRI). The goal was to better identify seizure-causing brain areas an…