CRANIOTOMY

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Trials to join now! 3 Not yet recruiting 2 Not yet finished but already full! 4 Completed 1

Could IV tylenol replace opioids after brain surgery?

Symptom relief Completed

This study tested whether giving intravenous acetaminophen (Tylenol) during and after brain surgery could reduce the need for opioid painkillers. 140 adults having open brain surgery were randomly assigned to receive either IV Tylenol or a placebo. The main goal was to see if mor…

Matched conditions: CRANIOTOMY

Phase: PHASE4 • Sponsor: Endeavor Health • Aim: Symptom relief

Last updated Jun 27, 2026 14:01 UTC

CRANIOTOMY

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Could IV tylenol replace opioids after brain surgery?