CONTRACTURE

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Not yet recruiting 1

Enzyme injection could loosen stiff joints in brain and spinal cord injuries

Symptom relief Not yet recruiting

This trial tests whether injecting collagenase—an enzyme that breaks down tough connective tissue—can reduce contracture (stiff, shortened muscles) and spasticity (uncontrolled muscle tightness) in people with neurological impairments like stroke, brain injury, or spinal cord inj…

Matched conditions: CONTRACTURE

Phase: EARLY_PHASE1 • Sponsor: The University of Texas Health Science Center, Houston • Aim: Symptom relief

Last updated Jul 11, 2026 00:00 UTC

CONTRACTURE

Get alerted when new CONTRACTURE trials appear

Enzyme injection could loosen stiff joints in brain and spinal cord injuries