CLL
Clinical trials for CLL explained in plain language.
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New combo aims to outperform standard therapy in CLL
Disease control OngoingThis phase 3 study tests whether a new combination of sonrotoclax and zanubrutinib works better than the current standard (venetoclax plus obinutuzumab) for people with untreated chronic lymphocytic leukemia (CLL). About 652 adults with CLL who need treatment but have not receive…
Matched conditions: CLL
Phase: PHASE3 • Sponsor: BeOne Medicines • Aim: Disease control
Last updated May 17, 2026 07:50 UTC
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New dosing schedule aims to make blood cancer drug safer
Disease control OngoingThis study tests different dosing schedules for the drug sonrotoclax in 56 adults with chronic lymphocytic leukemia (CLL). The goal is to find a safer way to start treatment and reduce the risk of tumor lysis syndrome, a serious side effect. Participants receive sonrotoclax in gr…
Matched conditions: CLL
Phase: PHASE1, PHASE2 • Sponsor: BeiGene • Aim: Disease control
Last updated May 11, 2026 20:48 UTC