BRCA1/2 MUTATION
Clinical trials for BRCA1/2 MUTATION explained in plain language.
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New hope for Hard-to-Treat pancreatic cancer: targeted drug combo shows promise
Disease control OngoingThis study compares a new three-drug combination (NABPLAGEM) against a standard two-drug chemo regimen for people with advanced pancreatic cancer that has spread and carries a BRCA or PALB2 gene mutation. The trial enrolls 10 participants whose cancer worsened after initial treat…
Matched conditions: BRCA1/2 MUTATION
Phase: PHASE2, PHASE3 • Sponsor: University Health Network, Toronto • Aim: Disease control
Last updated Jun 27, 2026 14:02 UTC
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Could a vaccine stop cancer before it starts in BRCA carriers?
Prevention OngoingThis early-stage study tests an experimental vaccine designed to prevent cancer in adults with BRCA1 or BRCA2 gene mutations. The vaccine is given alone or with another drug, followed by a mild electric pulse to help it enter cells. Researchers want to see if it is safe and wheth…
Matched conditions: BRCA1/2 MUTATION
Phase: PHASE1 • Sponsor: Abramson Cancer Center at Penn Medicine • Aim: Prevention
Last updated Jun 27, 2026 09:08 UTC