BETA-THALASSEMIA MAJOR
Clinical trials for BETA-THALASSEMIA MAJOR explained in plain language.
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Old drugs, new hope: could a thalidomide combo free thalassemia patients from transfusions?
Disease control Not yet recruitingThis study tests whether a combination of two drugs, thalidomide and hydroxyurea, can safely boost fetal hemoglobin levels in people with beta thalassemia major. The goal is to improve overall hemoglobin levels and reduce the need for regular blood transfusions. The trial include…
Matched conditions: BETA-THALASSEMIA MAJOR
Phase: NA • Sponsor: Riphah International University • Aim: Disease control
Last updated Jul 01, 2026 00:00 UTC
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Talking therapy could help thalassemia patients take their meds
Symptom relief Not yet recruitingThis study tests whether motivational interviewing, a type of counseling, can help adults with beta-thalassemia major follow their iron chelation therapy more consistently. Forty-five participants in Oman will receive three one-on-one sessions with a nurse over six to eight weeks…
Matched conditions: BETA-THALASSEMIA MAJOR
Phase: NA • Sponsor: Oman Ministry of Health • Aim: Symptom relief
Last updated Jun 27, 2026 14:01 UTC
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Could a microRNA predict dangerous blood transfusion reactions?
Knowledge-focused Not yet recruitingThis study will measure levels of a small molecule called microRNA-155 in 100 people who need regular blood transfusions, mostly due to beta thalassemia. The goal is to see if higher levels of this molecule are linked to the formation of harmful antibodies against donated blood. …
Matched conditions: BETA-THALASSEMIA MAJOR
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:04 UTC
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Greek study to measure daily life impact of iron overload drug
Knowledge-focused Not yet recruitingThis study looks at how thalassemia patients in Greece feel day-to-day while taking a standard iron-removing medicine called deferasirox. Researchers will survey 150 adults to measure their physical and mental well-being. The goal is to understand real-world quality of life, not …
Matched conditions: BETA-THALASSEMIA MAJOR
Sponsor: Elpen Pharmaceutical Co. Inc. • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC
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New study to reveal hidden body changes in kids with thalassemia
Knowledge-focused Not yet recruitingThis study looks at body composition—fat, muscle, and bone mass—in children aged 5 to 18 with beta thalassemia major who receive regular blood transfusions. Researchers will use a simple test to measure these body components and see how they relate to transfusion frequency, iron …
Matched conditions: BETA-THALASSEMIA MAJOR
Sponsor: Assiut University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC