AUGMENTATION

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Trials to join now! 1 Not yet finished but already full! 1 Completed 1

New drug candidate aims to calm restless legs when current meds backfire

Symptom relief Completed

This small study tested whether ecopipam, a drug that blocks a specific brain receptor, can help people with restless leg syndrome whose symptoms have gotten worse from their usual dopamine-based medication. Ten adults took either ecopipam or a placebo for six weeks, then switche…

Matched conditions: AUGMENTATION

Phase: PHASE1, PHASE2 • Sponsor: William Ondo, MD • Aim: Symptom relief

Last updated Jun 27, 2026 12:24 UTC

AUGMENTATION

Get alerted when new AUGMENTATION trials appear

New drug candidate aims to calm restless legs when current meds backfire