ANATOMIC STAGE IIIC BREAST CANCER AJCC V8
Clinical trials for ANATOMIC STAGE IIIC BREAST CANCER AJCC V8 explained in plain language.
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New drug combo tested for Tough-to-Treat advanced cancers
Disease control OngoingThis early-stage study is testing a new combination of two drugs, AZD8186 and docetaxel, for patients with advanced solid tumors that have specific genetic changes (PTEN or PIK3CB mutations). The main goals are to find the safest and most effective dose and to understand the side…
Matched conditions: ANATOMIC STAGE IIIC BREAST CANCER AJCC V8
Phase: PHASE1 • Sponsor: National Cancer Institute (NCI) • Aim: Disease control
Last updated Mar 30, 2026 14:31 UTC
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New hope for tough breast cancer: immune therapy trial targets aggressive cases
Disease control OngoingThis study tests whether adding the immunotherapy drug pembrolizumab to standard hormone therapy helps prevent cancer from returning in patients with a specific, aggressive type of breast cancer. It is for people whose cancer did not completely disappear after initial chemotherap…
Matched conditions: ANATOMIC STAGE IIIC BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Mar 24, 2026 12:02 UTC
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New vaccine trial aims to train body to destroy breast cancer cells
Disease control OngoingThis study is testing an experimental vaccine called STEMVAC in people with early-stage triple-negative breast cancer who have already finished their standard treatments. The goal is to see if the vaccine can safely 'wake up' the immune system to recognize and attack specific pro…
Matched conditions: ANATOMIC STAGE IIIC BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: University of Washington • Aim: Disease control
Last updated Mar 23, 2026 15:29 UTC
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New hope for High-Risk breast cancer patients: can two drugs beat one?
Disease control OngoingThis large study is testing whether adding the drug tucatinib to standard treatment (T-DM1) works better at preventing breast cancer from coming back. It is for people with a specific type of high-risk, HER2-positive breast cancer who still have some cancer cells after their init…
Matched conditions: ANATOMIC STAGE IIIC BREAST CANCER AJCC V8
Phase: PHASE3 • Sponsor: Alliance for Clinical Trials in Oncology • Aim: Disease control
Last updated Mar 18, 2026 14:42 UTC
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Early trial aims to tame tough cancers with Two-Pronged attack
Disease control OngoingThis early-stage study is testing a new drug, ALRN-6924, combined with a standard chemotherapy (paclitaxel) for people with advanced solid tumors that have spread or cannot be removed by surgery. The main goals are to find the safest and most effective dose of this combination an…
Matched conditions: ANATOMIC STAGE IIIC BREAST CANCER AJCC V8
Phase: PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated Mar 13, 2026 15:06 UTC
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New web portal aims to empower young women after breast cancer
Symptom relief OngoingThis study is testing a website called YES, designed to help young women who have finished breast cancer treatment. The goal is to see if using this website to track and manage symptoms improves their quality of life better than standard follow-up care. About 400 young survivors …
Matched conditions: ANATOMIC STAGE IIIC BREAST CANCER AJCC V8
Phase: NA • Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Symptom relief
Last updated Mar 18, 2026 14:41 UTC
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Can writing heal? study tests Pen-and-Paper therapy for breast cancer survivors
Symptom relief OngoingThis study is testing whether a brief writing program, designed specifically for Chinese immigrant culture, can help improve the quality of life and reduce stress for women who have survived breast cancer. Researchers are comparing three different types of writing exercises to se…
Matched conditions: ANATOMIC STAGE IIIC BREAST CANCER AJCC V8
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Symptom relief
Last updated Mar 17, 2026 13:08 UTC
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Can walking and strength training ease chemo side effects for seniors?
Symptom relief OngoingThis study is testing whether a home-based exercise program is practical and helpful for women aged 65 and older who are receiving chemotherapy for early-stage breast cancer. Participants follow a walking and strength training plan during their treatment. The main goal is to see …
Matched conditions: ANATOMIC STAGE IIIC BREAST CANCER AJCC V8
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Symptom relief
Last updated Mar 12, 2026 13:52 UTC
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Can we predict who gets nerve damage from chemo?
Knowledge-focused OngoingThis study aims to create a tool to predict which cancer patients are most likely to develop nerve damage (like tingling or numbness in hands and feet) from a common class of chemotherapy drugs called taxanes. Researchers will follow over 1,300 patients with breast, lung, or ovar…
Matched conditions: ANATOMIC STAGE IIIC BREAST CANCER AJCC V8
Sponsor: SWOG Cancer Research Network • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:12 UTC
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New tool aims to guide tough chemo choices for senior breast cancer patients
Knowledge-focused OngoingThis study aims to understand the information needs of women aged 65 and older with early-stage breast cancer who are deciding whether to have chemotherapy before or after surgery. Researchers are interviewing patients and doctors to develop a tailored decision support tool. The …
Matched conditions: ANATOMIC STAGE IIIC BREAST CANCER AJCC V8
Phase: NA • Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:30 UTC
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Can a simple test predict painful chemo side effects?
Knowledge-focused OngoingThis study aims to validate a genetic test that might predict which African American women with early-stage breast cancer are at higher risk for nerve damage (neuropathy) from common chemotherapy drugs. It also compares two different chemotherapy schedules to see which one might …
Matched conditions: ANATOMIC STAGE IIIC BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: ECOG-ACRIN Cancer Research Group • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:28 UTC
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Genetic testing trial aims to match breast cancer patients with right treatments
Knowledge-focused OngoingThis study is testing whether analyzing the genetic makeup of breast tumors can help predict which standard treatments will work best for individual patients. Researchers are enrolling 1,100 people with early-stage breast cancer to see if genetic testing can accurately identify t…
Matched conditions: ANATOMIC STAGE IIIC BREAST CANCER AJCC V8
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Mar 19, 2026 14:56 UTC
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Cancer survivors share their fertility struggles in major survey
Knowledge-focused OngoingThis study is a survey designed to understand the experiences of women who have survived breast or gynecological cancers when it comes to family planning and fertility. Researchers are asking over 1,400 survivors about their decisions, challenges, and use of fertility services af…
Matched conditions: ANATOMIC STAGE IIIC BREAST CANCER AJCC V8
Sponsor: M.D. Anderson Cancer Center • Aim: Knowledge-focused
Last updated Mar 02, 2026 15:22 UTC