X-linked reticulate pigmentary disorder

X-linked reticulate pigmentary disorder is an extremely rare skin disease described in only four families to date and characterized in males by diffuse reticulate brown hyperpigmentated skin lesions developing in early childhood and a variety of systemic manifestations (recurrent pneumonia, corneal opacification, gastrointestinal inflammation, urethral stricture, failure to thrive, hypohidrosis, digital clubbing, and unruly hair and flared eyebrows), while in females, there is only cutaneous involvement with the development in early childhood of localized brown hyperpigmented skin lesions following the lines of Blaschko. This disease was first considered as a cutaneous amyloidosis, but amyloid deposits are an inconstant feature.

Also known as: PDR, Partington disease, X-linked cutaneous amyloidosis, XLPDR, familial cutaneous amyloidosis, pigmentary disorder, reticulate, with systemic manifestations, X-linked, X-linked recessive, amyloidosis, familial cutaneous, pigmentary disorder, reticulate, with systemic manifestations

12 clinical trials for this condition and its sub-types, 0 tagged with X-linked reticulate pigmentary disorder itself.