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Werner syndrome

MONDO:0010196

A rare inherited syndrome characterized by premature aging with onset in the third decade of life and with cardinal clinical features including bilateral cataracts, short stature, graying and thinning of scalp hair, characteristic skin disorders and premature onset of additional age-related disorders.

Also known as: WS, Werner syndrome, Werner's syndrome, adult premature aging syndrome, adult progeria, WRN

2 clinical trials for this condition and its sub-types.

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Broader categories

Disease (680) Hereditary disease (176) Syndromic disease (25) Human disease (14) Developmental defect during embryogenesis (8) Premature aging syndrome (6) Autosomal recessive disease (4) Disease of genetic or genomic mechanism (2) Progeroid syndrome (2) Autosomal genetic disease (0)
Trials to join now! 1 Not yet recruiting 1
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  • New pill targets Hard-to-Treat cancers in early trial

    Disease control Recruiting now

    This early-phase trial is testing a new daily pill called NDI-219216 for people with advanced solid tumors that have not responded to standard treatments. The study will first check safety and side effects, then look at whether the drug can shrink tumors. About 134 participants w…

    Phase: PHASE1, PHASE2 • Sponsor: Nimbus Wadjet, Inc. • Aim: Disease control

    Last updated Jun 27, 2026 12:29 UTC

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