Thiamine-responsive megaloblastic anemia syndrome
MONDO:0009575Thiamine-responsive megaloblastic anemia (TRMA) is characterized by a triad of megaloblastic anemia, non-type I diabetes mellitus, and sensorineural deafness.
Also known as: Rogers syndrome, THMD1, TRMA, thiamine metabolism dysfunction syndrome 1, thiamine-responsive anemia syndrome, thiamine-responsive megaloblastic anemia syndrome, thiamine-responsive megaloblastic anemia with diabetes mellitus and sensorineural deafness, thiamine-responsive myelodysplasia
13 clinical trials for this condition and its sub-types.
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Blood transfusion thresholds tested to save elderly surgical patients
Disease control CompletedThis study tests whether giving blood transfusions more liberally (when hemoglobin drops to 9 g/dL) versus more restrictively (when it drops to 7.5 g/dL) reduces death and serious complications like heart attack, stroke, or kidney injury in patients aged 70 and older undergoing n…
Phase: PHASE3 • Sponsor: Johann Wolfgang Goethe University Hospital • Aim: Disease control
Last updated Jul 23, 2026 00:00 UTC
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Money and support groups boost HIV care in kenya
Disease control CompletedThis study tested a program that combines small loans and group support to help people with HIV in Kenya. The goal was to improve HIV medication adherence, mental health, and family relationships. 843 people took part, and the program aimed to reduce depression, anxiety, and PTSD…
Phase: NA • Sponsor: The University of Texas Medical Branch, Galveston • Aim: Disease control
Last updated Jun 27, 2026 08:06 UTC
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Anemia in kids may be tied to bigger hearts, study finds
Knowledge-focused CompletedThis study explored whether low hemoglobin (anemia) is linked to an enlarged heart (cardiomegaly) in children up to 18 years old. Researchers used chest X-rays and echocardiograms to check for heart enlargement in 56 anemic children. The goal was to better understand how anemia a…
Sponsor: Universitas Sumatera Utara • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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Neighborhood chats may help overcome COVID-19 testing mistrust
Knowledge-focused CompletedThis study tested whether weekly community-led group discussions could improve trust and openness to COVID-19 testing and vaccination. Fifty-seven adults from nine housing agencies took part in online meetings and completed surveys over six months. The goal was to see if peer-led…
Phase: NA • Sponsor: Old Dominion University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:08 UTC
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Neighborhood chats may help overcome COVID-19 testing mistrust
Knowledge-focused CompletedThis study tested whether weekly community-led group discussions about health topics could change how people feel about COVID-19 testing and vaccines. 49 adults from housing authority agencies took part in Zoom meetings and completed surveys over 18 weeks. The goal was to see if …
Phase: NA • Sponsor: Old Dominion University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:08 UTC