T-B+ severe combined immunodeficiency due to JAK3 deficiency
MONDO:0010938Severe combined immunodeficiency (SCID) T-B+ due to JAK3 deficiency is a form of SCID characterized by severe and recurrent infections, associated with diarrhea and failure to thrive.
Also known as: SCID, autosomal recessive, T-negative/B-positive type, T-B+ SCID due to JAK3 deficiency, T-B+ severe combined immunodeficiency due to JAK3 deficiency, T-cell negative B-cell positive severe combined immunodeficiency due to JAK3 deficiency, SCID, T cell-negative, B cell-positive, NK cell-negative, severe combined immunodeficiency T-cell negative B-cell positive due to janus kinase-3 deficiency, severe combined immunodeficiency, autosomal recessive, T cell-NEGATIVE, B cell-POSITIVE, NK cell-NEGATIVE
18 clinical trials for this condition and its sub-types.
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SCID stem cell trial pulled before it began
Disease control TerminatedThis study aimed to see if lower doses of chemotherapy drugs, with or without radiation, could safely prepare children and adults with SCID for a stem cell transplant. The goal was to help the donor cells take hold while avoiding severe side effects. However, the trial was withdr…
Phase: PHASE1, PHASE2 • Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: Disease control
Last updated Jun 27, 2026 08:00 UTC
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Newborn screening study aims to catch rare diseases at birth
Diagnosis OngoingThis study offers voluntary screening for newborns in North Carolina to detect a wide range of rare health conditions early. Using a small blood sample already collected at birth, the program tests for dozens of disorders, including spinal muscular atrophy, cystic fibrosis, and m…
Sponsor: RTI International • Aim: Diagnosis
Last updated Jul 03, 2026 00:00 UTC