Strabismus
MONDO:0003432Strabismus is the intermittent or constant misalignment of an eye so that its line of vision is not pointed at the same object as the other eye. Strabismus is caused by an imbalance in the extraocular muscles which control the positioning of the eyes. Strabismus is normal in newborns but should resolve by the time the baby is 6 months old. In older children with strabismus, the brain may learn to ignore the input from one eye, and this may lead to amblyopia, a potentially permanent decrease in vision in that eye if not corrected.
Also known as: squint, strabismus
46 clinical trials for this condition and its sub-types, 28 tagged with Strabismus itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
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Sub-types of Strabismus
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Exotropia 9 trials · 19 incl. sub-types
2 sub-types
- Alternating exotropia 11 trials
- Monocular exotropia 0 trials
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Intermittent squint 14 trials
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Esotropia 8 trials
3 sub-types
- Accommodative esotropia 1 trial
- Alternating esotropia 1 trial
- Monocular esotropia 0 trials
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Internuclear ophthalmoplegia 3 trials
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Conjugate gaze palsy 1 trial
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Mechanical strabismus 0 trials · 1 incl. sub-types
1 sub-type
- Brown syndrome 1 trial
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Cyclotropia 0 trials
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Hypertropia 0 trials
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Hypotropia 0 trials
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Monofixation syndrome 0 trials
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Paralytic strabismus 0 trials
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Eye muscle surgery showdown: which fix for wandering eyes works best?
Disease control CompletedThis trial compares two common surgical procedures for intermittent exotropia, a condition where one eye occasionally turns outward. Children aged 3 to 10 with basic or pseudo-divergence excess type exotropia are randomly assigned to receive either bilateral lateral rectus recess…
Sponsor: Jaeb Center for Health Research • Aim: Disease control
Last updated Jul 11, 2026 00:00 UTC
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Eye muscle surgery showdown: which fix for wandering eyes works best?
Disease control CompletedThis study compared two surgical methods to correct exotropia, a condition where one eye turns outward. In one group, a piece of the inner eye muscle was removed and reattached; in the other, the muscle was folded and shortened. Both groups also had the outer eye muscle loosened.…
Sponsor: Başakşehir Çam & Sakura City Hospital • Aim: Disease control
Last updated Jun 27, 2026 13:05 UTC
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Eye exercises after surgery may help keep eyes aligned
Disease control CompletedThis study looked at whether eye exercises after strabismus (crossed eyes) surgery help maintain eye alignment and control over time. Forty children aged 5 to 15 who had surgery and completed a 3-month exercise program were followed. Researchers measured eye deviation and control…
Sponsor: Amany Refaat Mohamed Abdel Wahid • Aim: Disease control
Last updated Jun 27, 2026 09:08 UTC
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Morning or evening patching for lazy eye? study seeks best timing
Symptom relief CompletedThis study tests whether patching the stronger eye in the morning (8-10 AM) or evening (5-7 PM) works better for improving vision in children with lazy eye (amblyopia). About 100 children aged 4-8 will wear an eye patch for 2-6 hours daily over 6 months. The goal is to see if tim…
Sponsor: Yarmouk University • Aim: Symptom relief
Last updated Aug 06, 2026 00:00 UTC
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Can a simple drug stop kids from waking up confused after eye surgery?
Symptom relief CompletedThis study tests whether giving sugammadex (a drug that reverses muscle relaxants) can lower the chance of children waking up agitated after strabismus (eye muscle) surgery. About 76 children aged 4 to 7 will be randomly assigned to receive either sugammadex or a standard drug (n…
Phase 4 • Sponsor: Konkuk University Medical Center • Aim: Symptom relief
Last updated Jul 17, 2026 00:00 UTC
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Deeper anesthesia may shield Kids' hearts during strabismus surgery
Symptom relief CompletedThis study tested whether giving children a deeper level of muscle relaxation during strabismus (crossed eyes) surgery could prevent a sudden drop in heart rate, known as the oculocardiac reflex. The trial involved 201 children aged 3 to 18 years. Researchers compared two levels …
Sponsor: Seoul National University Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC
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Which drug calms kids better after eye surgery?
Symptom relief CompletedThis trial tested two drugs, propofol and dexmedetomidine, to see which better prevents emergence agitation—a state of restlessness and crying—in children aged 3 to 7 after squint surgery. Eighty children were randomly given one of the drugs after anesthesia. The goal is to find …
Phase 4 • Sponsor: Ain Shams University • Aim: Symptom relief
Last updated Jun 27, 2026 07:53 UTC
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Small study reveals parents' struggles giving eye drops to toddlers after eye surgery
Knowledge-focused CompletedThis study interviewed 13 parents of children aged 2-6 who had strabismus (crossed eyes) surgery. Researchers wanted to understand how parents gave their children eye drops after surgery and how well the children cooperated. The goal is to learn from these experiences to improve …
Sponsor: Uludag University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC