Severe combined immunodeficiency due to CARD11 deficiency

Severe combined immunodeficiency due to CARD11 deficiency is a rare combined T and B cell immunodeficiency characterized by normal numbers of T and B lymphocytes, increased numbers of transitional B cells and hypo- to agammaglobulinemia, decreased numbers of regulatory T cells and defects in T-cell functions. It presents with severe susceptibility to infections, including opportunistic infections.

Also known as: immunodeficiency 11A, immunodeficiency type 11, CARD11 immunodeficiency, IMD11, IMD11A, immunodeficiency 11

2 clinical trials for this condition and its sub-types, 0 tagged with Severe combined immunodeficiency due to CARD11 deficiency itself.