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Schnitzler syndrome

MONDO:0018304

A rare, underdiagnosed disorder in adults characterized by recurrent febrile rash, bone and/or joint pain, enlarged lymph nodes, fatigue, a monoclonal IgM component, leukocytosis and systemic inflammatory response.

Also known as: chronic urticaria with gammopathy, chronic urticaria with macroglobulinemia, chronic urticaria with gammapathy

11 clinical trials for this condition and its sub-types.

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Broader categories

Disease (717) Rheumatic disorder (89) Connective tissue disorder (68) Syndromic disease (25) Autoinflammatory syndrome (21) Human disease (15) Disease by body system or component (0)

Trials to join now! 8 Not yet recruiting 1 Completed 2

New blood tests aim to unlock mysteries of rare inflammatory diseases

Knowledge-focused Not yet recruiting

This study aims to better understand rare autoinflammatory diseases by developing blood tests that measure inflammation markers. Researchers will analyze blood samples from 60 adults and children with these conditions. The goal is to identify specific inflammation pathways, which…

Sponsor: Hospices Civils de Lyon • Aim: Knowledge-focused

Last updated Jun 26, 2026 17:44 UTC