SAPHO syndrome

MONDO:0019266

SAPHO syndrome (acronym for Synovitis, Acne, Pustulosis, Hyperostosis and Osteitis) is an auto-inflammatory disease, mainly characterized by the association of neutrophilic cutaneous involvement and chronic osteomyelitis.

Also known as: PPHS, Pustulo-psoriatic hyperostotic Spondyloarthritis, synovitis, acne, pustulosis, hyperostosis, and osteitis syndrome, synovitis-acne-pustulosis-hyperostosis-osteitis syndrome, acquired hyperostosis syndrome, synovitis acne pustulosis hyperostosis osteitis, synovitis, acne, Pustlosis, hyperostosis, and osteomyelitis

13 clinical trials for this condition and its sub-types.

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Broader categories

Disease (717) Rheumatic disorder (89) Connective tissue disorder (68) Syndromic disease (25) Autoinflammatory syndrome (21) Human disease (15) Disease by body system or component (0)

Trials to join now! 9 Not yet recruiting 1 Completed 3

New blood tests aim to unlock mysteries of rare inflammatory diseases

Knowledge-focused Not yet recruiting

This study aims to better understand rare autoinflammatory diseases by developing blood tests that measure inflammation markers. Researchers will analyze blood samples from 60 adults and children with these conditions. The goal is to identify specific inflammation pathways, which…

Sponsor: Hospices Civils de Lyon • Aim: Knowledge-focused

Last updated Jun 26, 2026 17:44 UTC

SAPHO syndrome

Broader categories

New blood tests aim to unlock mysteries of rare inflammatory diseases