Rapidly progressive glomerulonephritis
MONDO:0017236Inflammation of the glomeruli that is characterized by a rapid loss in renal function with glomerular crescent formation observed on biopsy; it is often seen in patients with concomitant autoimmune disease, like Goodpasture's syndrome or systemic lupus erythematosus.
Also known as: RPGN, crescentic glomerulonephritis
7 clinical trials for this condition and its sub-types, 3 tagged with Rapidly progressive glomerulonephritis itself.
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Sub-types of Rapidly progressive glomerulonephritis
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New antibody aims to shield kidneys from autoimmune attack
Disease control Recruiting nowThis Phase 2 trial tests whether adding ALE.F02 to standard therapy can protect kidney function in people with ANCA-associated vasculitis, an autoimmune disease that attacks small blood vessels, often damaging the kidneys. About 80 participants will receive either a low, high, or…
Phase 2 • Sponsor: Alentis Therapeutics AG • Aim: Disease control
Last updated Aug 16, 2026 00:00 UTC
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Could a diabetes drug shield kidneys from autoimmune attack?
Disease control Recruiting nowThis trial investigates whether pioglitazone, a drug used for diabetes, can help protect the kidneys in people with ANCA-associated vasculitis—a rare autoimmune disease that causes inflammation of blood vessels, often damaging the kidneys. Participants receive either pioglitazone…
Phase 3 • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Disease control
Last updated Jul 03, 2026 00:00 UTC