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Protein-losing enteropathy
MONDO:0009174Pathological conditions in the intestines that are characterized by the gastrointestinal loss of serum proteins, including serum albumin; immunoglobulins; and at times lymphocytes. Severe condition can result in hypogammaglobulinemia or lymphopenia. Protein-losing enteropathies are associated with a number of diseases including intestinal lymphangiectasis; whipple'S disease; and neoplasms of the small intestine.
Also known as: protein-losing enteropathy, protein-losing enteropathy (disease), CHAPLE, complement hyperactivation, ANGIOPATHIC thrombosis, and PROTEIN-losing enteropathy, complement hyperactivation, Angiopathic thrombosis, and Protein-losing enteropathy, enteropathy, PROTEIN-losing
11 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
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Experimental drug offered to patients with rare gut condition
Disease control APPROVED_FOR_MARKETINGThis study provides compassionate access to pozelimab for people with CD55-deficient protein-losing enteropathy, a rare condition where the gut leaks proteins. The goal is to offer an experimental treatment option when no other therapies are available. Participants receive the dr…
Sponsor: Regeneron Pharmaceuticals • Aim: Disease control
Last updated Jun 27, 2026 07:57 UTC
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Lifesaving drug now available for kids with rare gut disease
Disease control APPROVED_FOR_MARKETINGThis program gives patients with CHAPLE disease, a rare and life-threatening immune disorder that causes protein loss from the gut, access to the experimental drug pozelimab. The goal is to provide treatment and monitor long-term safety. Participants must have a confirmed genetic…
Sponsor: Regeneron Pharmaceuticals • Aim: Disease control
Last updated Jun 27, 2026 07:56 UTC
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Massive data dive aims to improve GI care
Knowledge-focused ENROLLING_BY_INVITATIONThis study is a registry that will review medical records of 1,000 patients treated for benign or malignant gastrointestinal diseases between 2005 and 2030. Researchers will look at survival, symptoms like heartburn and swallowing trouble, and quality of life. The goal is to lear…
Sponsor: Methodist Health System • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC